Název projektu:
PS-FP7-SMEs IMMUNO2 - A novel biosensor concept for high-sensitive on-site screening of Legionella (11 HU 5010 3NEN)
Popis:
A Hungarian research centre invites SMEs to the FP7 Research for the Benefit of SME program. The aim of the project is to develop a fast high-sensitive on-site detection method for Legionella, a disease that represents a significant problem in Europe. The consortium is looking for medical equipment manufacturer SMEs to support the development, determination of systems specifications, testing and validation.
Legionella pneumophila is found in aquatic habitats, especially in potable water systems, cooling tower systems, heat exchanger systems. Human infection occurs through the inhalation of aerosols contaminated by Legionella spp. An estimated 8,000 to 18,000 people are stricken with Legionnaires' disease in EU-15 alone each year. Up to 30% of people who have Legionnaires' disease die.
In several European countries there are strong regulations requiring regular controls of water systems for Legionella, and there is a tendency for such regulation also in other countries. However, the conventional method for detection of Legionella is a complicated procedure involving isolation in a selective medium, which takes several days, requires a qualified laboratory, and high qualified personal. In addition, it presents several problems including the presence of viable but non-culturable pathogens, loss of viability after collection and the long time required for confirmation. In addition, detection is more difficult, since Legionella can be inhibited and masked by the rapid or abundant growth of other microorganisms. Available screening test kits are far away from the detections limits required by regulation. Thus there is a need for a fast high-sensitive on-site detection method without the need for highly qualified personal.
A consortium formed to meet this need of a system suitable for high-sensitive on-site screening of Legionella, successfully working on a novel biosensor concept based on rapid bio-techniques in the FP6 project IMMUNOLEGIO. The main objective was to develop a magneto resistive biosensor device for the detection of the magnetic bio-markers which were initially used for the concentration of the sample targeting to achieve a detection limit of 50 CFU/liter.
The former project ended with very good and validated results regarding the developed rapid bio-techniques as well as the automated sample preparation, but the magnetic read-out approach does not met the expectations regarding sensitivity. To meet the still existing need for highly-sensitive on-site detection in IMMUNO2 the consortium proposes building on the previously achieved immunological results the development of a novel portable fluorescent optical detection system completing the portable automatic sample preparation system, with a readout meeting the detection limit target. At this stage of the project we are looking for medical equipment manufacturers to contribute to the success of the project.
Technical Specifications / Specific technical requirements:
Call type, programme: FP7 "Research for the Benefit of SMEs"
Call identifier: FP7-SME-2012-BSG
Deadline: 06.12.2011
Proposal development stage: 80%, 1 partner missing
Requested EU funding: approx. 1 million euros
Percentage of EU funding: approx. 70%
Main task: support the development, determination of systems specifications, testing and validation
Legionella pneumophila is found in aquatic habitats, especially in potable water systems, cooling tower systems, heat exchanger systems. Human infection occurs through the inhalation of aerosols contaminated by Legionella spp. An estimated 8,000 to 18,000 people are stricken with Legionnaires' disease in EU-15 alone each year. Up to 30% of people who have Legionnaires' disease die.
In several European countries there are strong regulations requiring regular controls of water systems for Legionella, and there is a tendency for such regulation also in other countries. However, the conventional method for detection of Legionella is a complicated procedure involving isolation in a selective medium, which takes several days, requires a qualified laboratory, and high qualified personal. In addition, it presents several problems including the presence of viable but non-culturable pathogens, loss of viability after collection and the long time required for confirmation. In addition, detection is more difficult, since Legionella can be inhibited and masked by the rapid or abundant growth of other microorganisms. Available screening test kits are far away from the detections limits required by regulation. Thus there is a need for a fast high-sensitive on-site detection method without the need for highly qualified personal.
A consortium formed to meet this need of a system suitable for high-sensitive on-site screening of Legionella, successfully working on a novel biosensor concept based on rapid bio-techniques in the FP6 project IMMUNOLEGIO. The main objective was to develop a magneto resistive biosensor device for the detection of the magnetic bio-markers which were initially used for the concentration of the sample targeting to achieve a detection limit of 50 CFU/liter.
The former project ended with very good and validated results regarding the developed rapid bio-techniques as well as the automated sample preparation, but the magnetic read-out approach does not met the expectations regarding sensitivity. To meet the still existing need for highly-sensitive on-site detection in IMMUNO2 the consortium proposes building on the previously achieved immunological results the development of a novel portable fluorescent optical detection system completing the portable automatic sample preparation system, with a readout meeting the detection limit target. At this stage of the project we are looking for medical equipment manufacturers to contribute to the success of the project.
Technical Specifications / Specific technical requirements:
Call type, programme: FP7 "Research for the Benefit of SMEs"
Call identifier: FP7-SME-2012-BSG
Deadline: 06.12.2011
Proposal development stage: 80%, 1 partner missing
Requested EU funding: approx. 1 million euros
Percentage of EU funding: approx. 70%
Main task: support the development, determination of systems specifications, testing and validation
Požadavky na partnera:
Requested Cooperation: Joint further development
- Type of partner sought:SME
- Specific area of activity of the partner:
medical equipment manufacturers
- Task to be performed by the partner sought:
"Minor tasks in the R&D work as specifying the system details, supporting the RTD partners in validating and testing the results. Significant role in disseminating the project results and in the exploitation as they will get all the rights to use and distribute the results.
- Type of partner sought:SME
- Specific area of activity of the partner:
medical equipment manufacturers
- Task to be performed by the partner sought:
"Minor tasks in the R&D work as specifying the system details, supporting the RTD partners in validating and testing the results. Significant role in disseminating the project results and in the exploitation as they will get all the rights to use and distribute the results.
Obchodní firma/fyzická osoba:
Technologické inovační centrum s.r.o.
Sídlo/Místo podnikání:
Vavrečkova 5262
760 01 Zlín
760 01 Zlín
Kontaktní osoba:
Lenka Kostelníková
Email:
